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▀▓█▄ · the aggressive dominance · ▄ ▀▀▄ ▀▄▄ ▄░▄▓▀ ▀▓█▄▄▓█ jered
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█░ ·oO Sage Informatics ChemTK v4.2.1 Oo· ░█
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█░ release date: 2005-08-23 supplier: TEAM BLZ ░█
█░ disks: 2 cracker: TEAM BLZ ░█
█░ protection: Crippled os: WinALL ░█
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▀▀ ▄▀░ ░▓▀▀▀▀▓█ programnfo █▓▀▀▀▀▓░ ░▀▄ ▀▀
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█░ ChemTK is an easy-to-use graphical Windows toolkit providing chemists ░█
█░ the ability to visualize, organize, query, and analyze chemical ░█
█░ screening data. It functions both as a simple and convenient SD file ░█
█░ browser and as a powerful decision-support platform, offering ░█
█░ intuitive clustering and property-calculation capabilities, QSAR ░█
█░ model generation and virtual screening, R tables, similarity ░█
█░ analyses, and much more. ░█
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█░ Visualization ░█
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█░ With ChemTK you can conveniently visualize and browse the contents of ░█
█░ SD files. The graphical interface displays 2D molecular structures, ░█
█░ distributions of properties such as activity and molecular weight, ░█
█░ and tabular data that can be sorted, modified, or exported to file. ░█
█░ Users can also view descriptors, models, and R tables. ░█
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█░ Clustering ░█
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█░ ChemTK provides several automated methods for organizing data into ░█
█░ chemical families. Users can perform standard clustering to partition ░█
█░ molecules by common scaffold, or can organize data manually using ░█
█░ customized criteria. All subsequent analyses, such as model ░█
█░ generation, can be performed within any individual clusters. ░█
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█░ Querying ░█
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█░ Users can query their chemical data using a variety of flexible ░█
█░ search criteria, including Smarts patterns, pharmacophore signatures, ░█
█░ and molecular property constraints, and can combine any number of ░█
█░ individual queries to form logical expressions. Results are displayed ░█
█░ graphically via highlighting. ░█
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█░ Descriptors ░█
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█░ ChemTK offers a variety of descriptor types, including harmacophores, ░█
█░ structural fragments, ring systems, and bulk molecular properties ░█
█░ such as hydrogen-bond donor and acceptor counts. Derived descriptors ░█
█░ can be visualized graphically in the user interface, used internally ░█
█░ for similarity screening and QSAR model generation, or exported for ░█
█░ use with another data-mining software application. ░█
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█░ QSAR Models ░█
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█░ Users can generate predictive, easy-to-interpret QSAR models based on ░█
█░ the recursive partitioning method in conjunction with any of the ░█
█░ supported descriptor types. Models can be browsed visually to extract ░█
█░ structure-activity relationships or used for large-scale virtual ░█
█░ screening applications with external libraries. ░█
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█░ Similarity Analyses ░█
█░ ░█
█░ ChemTK allows users to measure structural similarities between a ░█
█░ molecule of interest and those molecules contained in either the open ░█
█░ document or an external file. Analyses can utilize any of several ░█
█░ descriptor types and similarity metrics, and the structural basis of ░█
█░ each derived score is provided in the form of molecular highlighting. ░█
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▀▀ ▄▀░ ▀▓▄ ░▓▀▀▀▀▓█ installnfo █▓▀▀▀▀▓░ ░▀▄ ▀▀
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█░ Run CHEMTK421.EXE and follow instructions. ░█
█░ ░█
█░ Copy BLZ-CHEMTK421-PATCH.EXE to your installed path and run it from ░█
█░ there. ░█
█░ ░█
█░ Use this Product Identification Number: CTK42100SRXP9803 ░█
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█░ ▀■· · · ·■▀ █▓█▀░▀■ ░█
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█░ After more than 4 years of nonstop releasing we are proud to present ░█
█░ you our 6000th 0day release, thus being only the second group ever ░█
█░ to reach this barrier. From the day BLiZZARD was formed in february ░█
█░ 1998 we have always been on the very top of the release rankings and ░█
█░ unlike many other groups we have almost never had any periods of ░█
█░ idleness or relaxation. ░█
█░ Over the years many friends joined us and we have grown to become ░█
█░ one of the biggest groups on the scene. New sections were created ░█
█░ (mp3/iso/pda) and all of them have been a great enrichment ░█
█░ for all of us, however unity and friendship have always remained, ░█
█░ even during times of upheaval and depression. All parts of BLiZZARD ░█
█░ work together with great enthusiasm and harmony. The spirit of a big ░█
█░ family has never vanished and has always given us a very unique ░█
█░ character. ░█
█░ Although we have always appreciated being one of the most active ░█
█░ release groups our primary concern has never been to rule the scene ░█
█░ but to spend a very nice time of our lives along with many good ░█
█░ friends. Friendship and fun will always be our most valuable ░█
█░ principles and according to them we will act. Over the years we have ░█
█░ neither been involved in any groupflames nor have we offended other ░█
█░ scene people without reason. Unlike many other groups we do not ░█
█░ believe in silly and childish flames, we treat our competitors ░█
█░ equal, however we want to give special props to the many old-school ░█
█░ groups which are still active and have survived all the recent busts ░█
█░ and problems. ░█
█░ Furthermore BLiZZARD has always offered its members a unique ░█
█░ atmosphere plus many benefits when it comes to release conditions. ░█
█░ We have shown the scene that you can be on the top without putting ░█
█░ your members under pressure, we simply believe in equality and ░█
█░ friendship. And, of course, many friendships, which go far beyond the ░█
█░ simple cracking business, have been formed. Every BLiZZARD member ░█
█░ will tell you what a great feeling and honour it is to be a part of ░█
█░ our family. It is such a great and motivating feeling to play a part ░█
█░ in it. ░█
█░ For the future we have already set many targets and we will reach ░█
█░ them for sure, expect many suprises from us. ░█
█░ BLiZZARD will never die, see you soon at the 7000th release :) ░█
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▀▀ ▄▀░ ▄▓▀ ░▓▀▀▀▀▓█ greetings █▓▀▀▀▀▓░ ░▀▄ ▀▀
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█░ greets fly out to all groups which actively and courageously work on ░█
█░ building better release conditions and thus keep the scene up. ░█
█░ special greets to our friends in: ░█
█░ acme - arctic - backlash - class - equinox - lnd - oddity ░█
█░ orion - tfa - toads - siechtum ░█
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▀▀ ▄▀░ ░▓▀▀▀▀▓█ retired █▓▀▀▀▀▓░ ░▀▄ ▀▀
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█░ we wish them the best in real life and thank them for all their ░█
█░ great work they have done for blizzard.. we'll never forget you!! ░█
█░ our fallen heroes: xxxxxx - xxxx - xxxxxxxxx - xxxxxxxxx - xxxx ░█
█░ xxxxxxxxxx - XxxxxxxX - Xxxxxx ░█
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▀▀ ▄▀░ ░▓▀▀▀▀▓█ ?joinin? █▓▀▀▀▀▓░ ▀▓▄ ░▀▄ ▀▀
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█░ We are a closed group, if we need you then we will contact you! ░█
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█░ Software worth using is worth buying.. keep this in mind! ░█
█░ ░█
█░ last update on: 2002.09.25 ░█
█░ .· ·. ░█
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▀▀▄░ ░ ▄█▓░ this .nfo drawn ░▓█▄ ░ ░▄▀▀
▀▀▀▀▀▀▓▀▀▀▀▀▀▀▀▀▀▓█░ by jered^blz! ░█▓▀▀▀▀▀▀▀▀▀▀▓▀▀▀▀▀▀
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