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▄▄ ░▄▄██▀ ░▄█▄ . ·` N i T R O U S '· . ▀▓█▄▄░ ░▄▄
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░ ▀▀█████▓░ ▀███▄ ▀▓▄█▓█▀ ░ ░▓████▓▀F0sT░
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░ ■ ▄ ■ ■ ▄ ■ ░
Bio-Loom v1.0
(C)
BioByte
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██▀ ▄▓██▓ SUPPLiER..........................: NiTROUS ▓██▓▄ ▀██
███ ████ CRACKER...........................: NiTROUS ████ ███
████▄█████▄ PACKAGER..........................: NiTROUS ▄█████▄████
░▓███▀██▀░ ▀ TESTER............................: NiTROUS ▀ ░▀██▀███▓░
▀▓█▄░▄██▄▀ RELEASE DATE......................: 03/23/05 ▀▄██▄░▄█▓▀
▓████▓█▄ RELEASE TYPE......................: Incl Keymaker ▄█▓████▓
▄ ░███▒██▓ DiSKS.............................: 03 X 4,77MB ▓██▒███░ ▄
▓▄ ▓█▓░███▓ PROTECTiON........................: MD5/Serial ▓███░▓█▓ ▄▓
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▓▀▄ . ·` RELEASE iNFORMATiON '· . ▄▀▓
░ ▄ ▄ ░
BioByte's new Bio-Loom program weaves
several different threads of data into a
cohesive whole.
Of course, Bio-Loom still calculates
hydrophobic and molecular refractivity
parameters via CLOGP & CMR, calculations
which have been the world standard for
decades, but it now has the ability to
access BioByte's entire Thor Masterfile
database, which includes over 60,000
measured log P and log D values (in many
solvent systems), as well as 14,000
pKas, including associated references.
The biological activity searches are now
much more powerful than before. Hundreds
of searchable biological activity types,
both TARGETS (e.g. HmgCoA reductase
inhibitors) and RESULTS (e.g.
anti-hyperlipidemic) lead to thousands
of active structures, many of which have
been carefully studied via QSAR.
For example, say you are investigating
cognition enhancers (105 hits). What are
the structural relationships to
nootropics (68)? Cerebral vasodilators
(23)? Anti-Alzheimers (55)? Bio-Loom can
show you.
You are also interested in the targets
associated with each result. Which of
the above are AcChE Inhibitors?
Muscarinic Agonists? Bio-Loom can show
you.
The entire QSAR Database is now
available for easy and flexible
searching online, accessible only
through the Bio-Loom program! Click here
for an introduction, which shows how one
might discover valuable QSAR data on
cox-2 inhibitors such as Vioxx,
Celebrex, and Arcoxia, and some of the
interesting questions that such data
could pose for drug developers.
░ URL: http://www.biobyte.com
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▒▀█▄▀█▓▓▄▄▄█▓▀ ▄░▄ . ·` iNSTALL iNFO '· . ██▓ ▒
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1.) Unpack.
2.) Install.
3.) Use the included keymaker to register.
4.) Enjoy.
/NiTROUS
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▒▀█▄▀█▓▓▄▄▄█▓▀ ▄░▄ . ·` NEWS & GREETS '· . ▄░▄ ▄▓██▓
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█▀ ▄ ▀█▄ NiTROUS TEAM is looking for: ░▀▒░
▓░▀▓▀ █▓░ ▓▄░ ░
░ ░ █▀░ + Talented crackers (NO Newbie's!) █▓▄
░ ▀ ▓▀ + Talented coders (ASM/C++/Delphi) ▀█▓
░ ▒ + 50+mbit box owners (Dumps/HQ's) ▓▄▀ ░
░ ░ + Software Suppliers (Unreleased apps) ▒▓█
░ + Anything else that might interest us ░░▒▓ ░
░ ░ ░▒ ░
░ ▒ GREETiNGS to: ░░ ░
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░ ░ █▄░ . ·` CONTACT iNFO '· . ░▄█ ▓
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█▄ ▀ ▄█▀ E-mail: nitrous[at]merseymail[dot]com ▀█▄ ▀ ▄█
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██ ░▓▀ ▄██▀▀░ ▀▓█ ASKEE iLLUSiON █▓▀ ░▀▀██▄ ▀▓░ ██
██ █▄ ▀▓█▄▀ ▀▀ ▀ . ·` F0sT/sAc/ACiD '· . ▀ ▀▀ ▀▄█▓▀ ▄█ ██
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▀█ ▄░▄ "Imagination is more important than knowledge..." ▄░▄ █▀
▄ ▀ -Albert Einstein (1879-1955) ▀ ▄